hey cherishu2, I wouldn't be surprised if it come out that keratoconus is a hereditary endocrine disease, just the fact's haven't been proven but it's staring us all in the face young teenagers, pregnant women maybe if us human males were castrated before puberty kerotoconus would not be so prevalent, but i know i wouldn't want to volunteer for that surgical procedure lol
Still loving this KC mouse!!!
tom
KC genetics hereditary link discussion (now inc a KC mouse!)
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- tommy.dean
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- Keratoconus: Yes, I have KC
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- Andrew MacLean
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- Keratoconus: Yes, I have KC
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No pictures here, just science, but the paper is interesting and does open possible non-surgical therapies:
http://www.pnas.org/cgi/reprint/102/46/16795.pdf
Andrew
http://www.pnas.org/cgi/reprint/102/46/16795.pdf
Andrew
Andrew MacLean
- tommy.dean
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- Keratoconus: Yes, I have KC
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Andrew just read that study it's made me understand more about keratoconus, after my first penetrating keratoplasty i took part in a study on nerve regrowth in transplanted cornea's they were testing corneal sensitivity at different stages after the nerves had been severed. I was told that i was the only person taking part whose nerves regrew so fast, so maybe thats why contact lenses were such a problem for me maybe there are two set's of keratoconics a set where the nerves are present in normal amounts or more (I'm guessing this means the absence of nerve growth receptor TrkA isn't always true) but for some reason a breakdown/ over presence in isoforms still occurs, and another set as found in that study where the absence of this nerve growth receptor directly effects the isoforms. It's funny you've posted this study now, as only last night i was emailing manchester university trying to find out if taym finished his study and what results he got, i'm presuming though i would have been his anomalies in his study. When i manage to get the data and results there sure to be posted on here, so we can look at them and come to whakey conclusions
Cherishu2 let's hope there's no young males with KC in your area , not many people would agree with me saying its an endocrine disease though it's a very very controversial subject.
tom
Cherishu2 let's hope there's no young males with KC in your area , not many people would agree with me saying its an endocrine disease though it's a very very controversial subject.
tom
Last edited by tommy.dean on Wed 20 Jun 2007 10:17 pm, edited 1 time in total.
- Lisa Nixon
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KC is definately hereditary in my case. My natural mother had it, (I'm adopted but her records state that she had very poor vision and wore strong glasses). I have it. My son, now 26 has it. My grandson is 6 months old tomorrow and I'm praying that he doesn't get it.
Only Robinson Crusoe got everything done by Friday!!
- Lisa Nixon
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- tommy.dean
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- Keratoconus: Yes, I have KC
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- Location: Blackburn
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- John Smith
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- Keratoconus: Yes, I have KC
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- tommy.dean
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- Keratoconus: Yes, I have KC
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- Location: Blackburn
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Hey john, I thought i was the only 1 that hung round on the forums at this time lol, I've never read anybody stating that after 3 generations it subside's before, it's a very bold statement considering how varied KC is thats all i can say for now, how many patients were part of the study and at what stages where there keratoncons do you know?
tom (the nocturnal keratoconic lol )
tom (the nocturnal keratoconic lol )
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